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Burrin
Lab -- Postdoctoral Fellows |
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 Steven Kim, D.O.
B.S. University of California, San Diego (BioChem) 1996
D.O. Chicago College of Osteopathic Medicine. Downers Grove, IL 2001.
I joined the Burrin lab in July 2006 as a Pediatric Gastroenterology, Hepatology, and Nutrition fellow at Baylor College of Medicine. My research has focused on
evaluating the efficacy of Lactobacillus reuteri in preventing Salmonella typhimurium induced enteritis in weanling pigs. The potential applicability of probiotics
in treating and preventing various disease states is broad and thus relevant to the pediatric patients I care for. These patients include those with inflammatory
bowel disease, irritable bowel syndrome, infectious diarrhea, chronic abdominal pain, and infantile colic to name a few. The challenge is in understanding the
mechanism(s) whereby probiotics induce their effects- whether by barrier effect, anti-inflammatory/cytotoxic properties, nutrient competition.
 Caroline Bauchart-Thevret, Ph.D.
April, 2007-current
Ph.D. Human Nutrition, Auvergne University in Clermont-Ferrand, France, 2006
I joined Doug Burrin's lab in April 2007 as a Postdoctoral Associate to work on a project related to the metabolism of sulfur amino acids (SAAs) in the neonatal gut.
My aim is to determine the role of SAAs (methionine and cysteine) on intestinal growth and antioxidant function in the neonate using the neonatal piglet model.
My project includes a variety of stable isotopic tracer techniques to estimate the whole body fluxes of methionine and cysteine metabolism, including
transmethylation, remethylation and transsulfuration, and the technique of laser-capture microdissection to quantify the mucosal glutathione status in
proliferating crypt and differentiated villus mucosal epithelial cells. I am also using a porcine intestinal epithelial cell culture model (IPEC-J2) to
establish the metabolic significance of SAA metabolism in the maintenance of intestinal epithelial cell redox status and cell survival.
 Patrycja Puiman, M.D.
July, 2007 – July, 2008
M.D. Medical School, University of Maastricht, 2004
Ph.D. Neonatology-Nutrition, Erasmus Medical Center - Sophia's Children's Hospital Rotterdam, The Netherlands, 2006-current
I came to Doug Burrin's lab in July 2007 to work on a collaborative project with my mentor, Johannes van Goudoever. The aim of my project is to establish the influence
of the intestinal microflora on the neonatal gut and amino acid availability by using the neonatal piglet model that has been developed in the Burrin lab. Furthermore,
we want to determine whether manipulation of the gut flora by supplementation of antibiotics, prebiotics and probiotics will improve nutrition and growth during early
postnatal development. In the future, similar studies might be conducted in (preterm) neonates at the Sophia Children's Hospital in Rotterdam the Netherlands.
This work will become part of my PhD dissertation thesis and maybe helpful in my clinical practice at the neonatal intensive care unit.
Maaike Riedijk, M.D.
October, 2003 – June, 2004
M.D. Medical School, University of Utrecht , 2000
Ph.D. Neonatology-Nutrition, Erasmus Medical MC, Sophia's Children's Hospital Rotterdam, 2003-current
I came to Doug Burrin's lab in October 2003 to work on a collaborative project with my mentor, Johannes Van Goudoever. The aim of the project is to determine the metabolic fate of dietary methionine in the neonatal gut using the infant
pig model used in the Burrin Lab. We are especially interested in establishing the role of the gut in whole body transmethylation and transsulfuration of dietary methionine. This work will become part of my PhD dissertation thesis
and will be combined with similar clinical studies with methionine tracers in preterm infants to be conducted at the Sophia Children's Hospital.
 Nancy Benight
January 2007 – July 2010
B.A. Zoology, Miami University-Ohio in 2006
My undergraduate degree was in zoology with a minor in molecular biology. As an undergraduate, I also spent one year researching the effects of growth hormone on PPARγ expression
in a murine model of colitis at Cincinnati Children’s Hospital Research Foundation. Currently, I am a graduate student in the Translational Biology and Molecular Medicine
program through Baylor College of Medicine and joined the Burrin lab in January 2007. My graduate project involves investigation of the role of methionine metabolism in
pediatric inflammatory bowel disease and how alterations in this pathway contribute to these diseases. We are using mouse models of colitis and stable isotopic tracer and
cell molecular approaches.
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